The latest version of Darwine and the newest version of XQuartz allow Wine on the mac to actually serve some kind of purpose (3D stuff).
The latest version of Darwine is available here (unofficial of course, as the official Darwine developers appear to be MIA): http://www.kronenberg.org/darwine/
And XQuartz, the unofficial (though Apple does use part of it) X11 update for the Mac: http://xquartz.macosforge.org/trac/wiki